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Filtered Search Results
Aobchem 7-Chloro-2-methylquinoline | ≥95% | CAS 4965-33-7 | C10H8ClN | 100g
7-Chloro-2-methylquinoline | ≥95% | CAS 4965-33-7 | C10H8ClN | 100g
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Medchemexpress LLC FX-06 1mg | 88650-17-3 | 1MG
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FX-06 (Fibrin-derived peptide B 15-42) is a fibrin Bbeta chain-derived peptide FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling FX-06 can be used in the research of ischemia/reperfusion injury Dengue shock syndrome (DSS)[1 [2 [4
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eMolecules 82019-32-7 | 7-Bromo-1-methyl-1H-quinoxalin-2-one | MFCD10000855 | 250mg
Ambeed | 7-Bromo-1-methyl-1H-quinoxalin-2-one | 250mg | 600833751 | A206593 | 82019-32-7 | MFCD10000855 | 239.072 | C9H7BrN2O
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Medchemexpress LLC DD-03-171 | 2366132-45-6 | 98.7% | 1 ML
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PROTAC BTK degrader supplied as a concentrated solution for use in biochemical and cellular research. Provided as a small-volume, high-concentration stock suitable for in vitro assays; reported purity supports use in assay development and preclinical studies.
- Provided as a 10 mM solution in DMSO, 1 mL.
- Induces selective degradation of Bruton's tyrosine kinase (BTK) in cellular models.
- High reported purity, suitable for biochemical and cell-based assays.
- Chemical formula C55H62N10O8 and molecular weight 991.14 g/mol.
- Packaged for research applications requiring small-volume, concentrated stocks.
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Medchemexpress LLC Methyl 3,3-dimethoxypropionate | 7424-91-1 | MFCD00010650 | ≥98.0% | 148.16 g·mol^-1 | C6H12O4 | 100 G
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Methyl 3,3-dimethoxypropionate is an organic methyl ester used as a building block and intermediate in organic synthesis and life-science research. It is commonly employed in the preparation of derivatives and in multi-step synthetic sequences where a protected aldehyde equivalent is required.
- High purity (≥98.0%) for research and synthesis.
- Serves as a methyl ester building block in organic synthesis.
- Useful as a protected aldehyde equivalent in multi-step syntheses.
- Available in multiple pack sizes for lab-scale work.
- Molecular formula C6H12O4 and molecular weight 148.16 g·mol^-1.
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Medchemexpress LLC DYB-03 | 2982792-85-6 | 99.5% | 479.56 | 1 ML
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DYB-03 is an orally active HIF-1α/EZH2 inhibitor. It inhibits the migration, invasion, and angiogenesis of lung cancer cells and HUVECs both in vitro and in vivo. Additionally, DYB-03 induces apoptosis in A549 and H460 cells that are resistant to 2-ME2 and GSK126.
- Oral active HIF-1α/EZH2 inhibitor
- Inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs (in vitro and in vivo)
- Induces apoptosis in 2-ME2- and GSK126-resistant A549 and H460 cells
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Apexbio Technology LLC IAA-94 54197-31-8 25mg
IAA-94 (CAS 54197-31-8) is a small-molecule inhibitor of epithelial chloride channels modulating cellular electrophysiological properties by disrupting chloride ion transport Experimental studies have demonstrated that IAA-94 can interfere with interactions involving the negative factor (Nef) protein during infection indicating its capacity to modulate Nef-mediated processes Due to its specificity in targeting chloride channels IAA-94 is widely utilized in investigations of ion channel-related signaling pathways in tumor cells and serves as a valuable tool in studies of cell electrophysiology and infection mechanisms
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Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.
- Selective PROTAC PTPN2 degrader
- Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
- Promotes T cell activation
- Amplifies IFN-γ-mediated anticancer activity
- Composed of a PTPN2 ligand, a linker, and a VHL ligand
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Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 25 MG
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Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor used in research to block proteolytic shedding of cell-surface molecules such as L-selectin and TNF-α. It demonstrates sub-micromolar to low-micromolar activity in human and mouse immune cells and is supplied as a high-purity solid for laboratory experiments.
- Potent inhibition of L-selectin shedding in immune cells.
- Active against TNF-α shedding in monocytes.
- High purity suitable for biochemical and cellular assays.
- Available in multiple pack sizes including small-milligram quantities.
- Provided with datasheet, SDS, and COA for quality traceability.
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Medchemexpress LLC Al-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 10MG
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AL-611 is a research-grade small-molecule inhibitor described by the manufacturer as an HCV protease inhibitor intended for laboratory research use. It is supplied as a white to off-white solid and is characterized by a high reported purity and defined molecular properties.
- Potent HCV protease inhibitor for laboratory research.
- High purity (99.93%).
- White to off-white solid, suitable for analytical and biological assays.
- Molecular weight 614.54 Da; molecular formula C25H33F2N6O8P.
- Datasheet, certificate of analysis, and safety data sheet available.
- Intended for research use only, not for human or veterinary use.
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eMolecules 79025-28-8 | 3,4-Dimethoxy-2-nitrobenzoic acid | Ambeed | MFCD00074884 | 227.172 | C9H9NO6 | 95.000 | COc1ccc(C(O)=O)c(c1OC)[N+]([O-])=O | 100mg | 525226340
3,4-Dimethoxy-2-nitrobenzoic acid | Ambeed | 79025-28-8 | MFCD00074884 | 227.172 | C9H9NO6 | 95.000 | COc1ccc(C(O)=O)c(c1OC)[N+]([O-])=O | 100mg | 525226340
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Apexbio Technology LLC parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] 25mg
Parathyroid hormone (7-34) is a polypeptide antagonist targeting parathyroid hormone receptors (PTH1R and PTH2R) It is derived from Homo sapiens and Macaca fascicularis and is designed to modulate PTH receptor activity thereby influencing calcium and phosphate homeostasis Parathyroid hormone (7-34) exerts its biological activity primarily through competitive interaction with PTH receptors affecting absorption processes in bone kidney and intestinal tissues Based on these pharmacological properties parathyroid hormone (7-34) holds research potential in studies of mineral metabolism bone remodeling and calcium-phosphate balance disorders
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TARGETMOL CHEMICALS INC RIAA-94 5MG
Also available in 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. R(+)-IAA-94 (R(+)-Methylindazone) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef). purity: 99%
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Medchemexpress LLC Rgw-611 | 6497-78-5 | 98.0% | 226.24 | C9H14N4O3 | 10 MG
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RGW-611 is a morpholine-derived research compound reported to enhance radiation-induced cell death in hypoxic V79-379A cells and to stimulate fatty acid synthesis. The compound is intended for laboratory research use and includes formulation, solubility, and storage guidance to support in vitro and in vivo preparation.
- Enhances radiation-induced cell death in hypoxic V79-379A cells.
- Stimulates fatty acid synthesis.
- Chemical formula C9H14N4O3; molecular weight 226.24.
- High DMSO solubility: 125 mg/mL with ultrasonic/warming to 60°C.
- In vivo vehicle solubility ≥2.08 mg/mL reported for multiple formulations.
- Storage: 4°C protected from light; in solvent -80°C (6 months) or -20°C (1 month).
- Available in small research pack sizes with stock solution preparation volumes provided.
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Apexbio Technology LLC prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] 25mg
Prostate apoptosis response protein PAR-4 2-7 is a short peptide targeting transcriptional regulation pathways It is designed to modulate transcription factor activity thereby influencing apoptosis mechanisms particularly in prostate cells PAR-4 2-7 exerts its biological activity primarily through interaction with transcription factors via a leucine zipper zinc finger domain facilitating apoptosis in transformed or malignant cells while sparing normal cells Based on these properties PAR-4 2-7 holds research potential in studies investigating tumor suppression mechanisms and transcription-mediated apoptosis regulation in oncology and therapeutic research
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